Influence of External Electrostatic Fields on Enzyme Systems of Phospholipid Deacylation

G. G. Arzruny^1*, T. B. Batikyan², and Yu. V. Tadevosyan²

¹Geratsi Yerevan State Medical University, ul. Koryuna 2, Yerevan, 375025 Republic of Armenia; E-mail: root@emil.arminco.com

²Institute of Molecular Biology, National Academy of Sciences of Republic of Armenia, ul. Hasratyana 7, Yerevan, 375014 Republic of Armenia

^* To whom correspondence should be addressed.

Received October 9, 1998; Revision received April 28, 1999

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The in vivo effect of external electrostatic field (200 kV/m for 1 h) on the activity of type A phospholipases and lysophospholipases of erythrocyte and mitochondrial membranes was studied. The electrostatic field exposure activated membrane-associated deacylation of phosphatidylcholine fraction in erythrocyte membranes.

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KEY WORDS: electrostatic field, biomembranes, lipid modification, deacylation, phospholipase, lysophospholipase

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