In memory of my teacher Boris F. Poglazov
2Bach Institute of Biochemistry, Russian Academy of Sciences, Leninsky pr. 33, Moscow 119071, Russia; fax: (7-095) 954-2732; E-mail: firstname.lastname@example.org
Received July 9, 2004
Evolution of notions on the molecular mechanism of muscle contraction and other events based on the actin-myosin interaction, from the middle of XX century to the present time, is briefly reviewed, including recent views on the functioning of the myosin head as a molecular motor. The results of structural and functional studies on the myosin head performed by the author and his colleagues using differential scanning calorimetry are also reviewed.
KEY WORDS: biological motility, myosin, actin, actomyosin, differential scanning calorimetry