2Joint Italian-Russian Institute of Ecological Research and Education, University of Palermo, Palermo 90128, Italy
3Department of Cell Biology and Histology, Faculty of Biology, Lomonosov Moscow State University, 119992 Moscow, Russia
* To whom correspondence should be addressed.
Received January 27, 2005; Revision received February 17, 2005
In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of discreteness of structural levels of DNA compactization.
KEY WORDS: chromatin, chromosome, mitosis, banding, chromomere, chromonema