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MINI-REVIEW: Mitochondrial Glutathione

V. I. Kulinsky* and L. S. Kolesnichenko

Irkutsk State Medical University, ul. Krasnogo Vosstaniya 1, 664047 Irkutsk, Russia; fax: (3952) 24-0826; E-mail: kulinsky@pp.irkutsk.ru

* To whom correspondence should be addressed.

Received March 3, 2007; Revision received April 7, 2007
Many functions of mitochondrial GSH are significantly different from those of cytosolic GSH. This review considers the peculiarity of functions of mitochondrial GSH and enzymes of its metabolism, especially glutathione peroxidase 4, glutaredoxin 2, and kappa-glutathione transferase.
KEY WORDS: glutathione, enzymes of GSH metabolism, mitochondria

DOI: 10.1134/S0006297907070024