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Molecular Mechanisms of Neuroplasticity: An Expanding Universe


N. V. Gulyaeva

Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, 117485 Moscow, Russia; E-mail: nata_gul@mail.ru

Received November 28, 2016
Biochemical processes in synapses and other neuronal compartments underlie neuroplasticity (functional and structural alterations in the brain enabling adaptation to the environment, learning, memory, as well as rehabilitation after brain injury). This basic molecular level of brain plasticity covers numerous specific proteins (enzymes, receptors, structural proteins, etc.) participating in many coordinated and interacting signal and metabolic processes, their modulation forming a molecular basis for brain plasticity. The articles in this issue are focused on different “hot points” in the research area of biochemical mechanisms supporting neuroplasticity.
KEY WORDS: brain, neuroplasticity, synaptic plasticity, proteins, enzymes, receptors, biochemical mechanisms, signal transduction

DOI: 10.1134/S0006297917030014