Structure of Teichoic Acid of the Cell Wall of Streptomyces sparsogenes VKM Ac-1744T
A. S. Shashkov1, E. M. Tul'skaya2, A. A. Grachev1, L. I. Evtushenko3, O. V. Bueva3, and I. B. Naumova2*
1Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky pr. 47, Moscow, 117913 Russia; fax: (095) 135-53282School of Biology, Lomonosov Moscow State University, Moscow, 119899 Russia; fax: (095) 939-4309
3Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, 142292 Russia; fax: (095) 923-3602
* To whom correspondence should be addressed.
Received January 12, 1998; Revision received May 28, 1998
The cell wall of Streptomyces sparsogenes VKM Ac-1744T contains a teichoic acid of 1,3-poly(glycerol phosphate) type. The polymer is composed of about 11 repeating units of the following structure:
The structure was not identified in gram-positive bacteria previously. The data are in agreement with DNA-relatedness between Streptomyces sparsogenes and Streptomyces hygroscopicus species and suggest the species-specificity of teichoic acid structure in the studied streptomycetes group.
KEY WORDS: cell wall, teichoic acid, Streptomyces, NMR-spectroscopy
