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REVIEW: The Role of Lysosphingolipids in the Regulation of Biological Processes


E. V. Dyatlovitskaya

Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, 117997 Moscow, Russia; E-mail: dyatl@ibch.ru

Received December 18, 2006; Revision received January 24, 2007
This review summarizes data on the role of lysosphingolipids (glucosyl- and galactosylsphingosines, sphingosine-1-phosphate, sphingosine-1-phosphocholine) in the regulation of various biological processes in normal and pathological states.
KEY WORDS: galactosylsphingosine, glucosylsphingosine, lactosylsphingosine, sphingosine-1-phosphate, sphingosine-1-phosphocholine, lysosphingolipid

DOI: 10.1134/S0006297907050033