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REVIEW: Structural Aspects of Ribosomal RNA Recognition by Ribosomal Proteins

A. D. Nikulin

Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russia; E-mail: nikulin@vega.protres.ru

Received July 26, 2017; Revision received August 8, 2017
This review is focused on the structural aspects of interaction between ribosomal proteins and ribosomal RNA in bacterial ribosomes and complexes of ribosomal proteins with specific fragments of ribosomal RNA. Special attention is given to the recognition of specific spatial architecture of the double-stranded ribosomal RNA by ribosomal proteins and to the role of unstructured protein regions in stabilization of distant ribosomal RNA segments.
KEY WORDS: ribosome structure, ribosomal proteins, ribosomal RNA, RNA–protein recognition, double-stranded RNA, unstructured proteins

DOI: 10.1134/S0006297918140109